Suspect poisoning? US: ASPCA Poison Control (888) 426-4435 · UK: 01202 509 000 · Severe symptoms → nearest emergency vet now.

Paracetamol Poisoning in Dogs and Cats

Paracetamol (acetaminophen) is extremely toxic to cats and can be dangerous for dogs, causing severe damage to red blood cells and the liver.

Last reviewed: 2026-09-05 · Reference ranges: ASPCA, Pet Poison Helpline & Merck Veterinary Manual

Treat this as a potential emergency — not a "wait and see" situation.
Contact your vet before symptoms even appear.

US: ASPCA Animal Poison Control (888) 426-4435 · Pet Poison Helpline (855) 764-7661

UK: Veterinary Poisons Information Service 01202 509 000

Why is Paracetamol Toxic to Pets?

Pets, especially cats, lack sufficient levels of a specific liver enzyme needed to safely metabolize paracetamol.

This leads to the accumulation of toxic compounds that irreversibly damage red blood cells, preventing them from carrying oxygen (methemoglobinemia), and cause severe, potentially fatal liver damage.

Even a single small tablet can be lethal for a cat, and doses considered safe for humans can poison dogs.

Why speed matters

Delaying care significantly worsens outcomes. Some signs appear hours or days later, so "looks fine right now" is not a reason to wait.

Symptoms of paracetamol poisoning

  • Difficulty breathing, rapid breathing, or blue/grey gums (signs of oxygen deprivation)
  • Swelling of the face, paws, or neck
  • Lethargy, weakness, and collapse
  • Vomiting, drooling, and loss of appetite
  • Brown or chocolate-colored gums (methemoglobinemia)
  • Jaundice (yellowing of the skin, gums, or eyes) indicating liver damage

What to do right now

  1. Call your veterinarian or a pet poison control center immediately. This is a time-critical emergency.
  2. Do NOT induce vomiting unless specifically instructed by a veterinary professional.
  3. If possible, provide the product name, strength (mg), and estimated amount ingested.
  4. Do not give any other medications or home remedies.
  5. Be prepared to transport your pet to the veterinary clinic for urgent treatment, which may include inducing vomiting (if safe), administering an antidote (acetylcysteine), and supportive care.
If your pet shows any of the signs above, go to the nearest emergency vet now and call ahead.

Sources & further reading

  • ASPCA Animal Poison Control — pet poison database & dosage references
  • Pet Poison Helpline — toxicology triage guidelines
  • Merck Veterinary Manual — toxicology monographs
  • Vets Now (UK) — emergency toxicosis guidance

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Frequently asked questions

Is Paracetamol Poisoning in Dogs and Cats poisonous to a dog or cat?

Pets, especially cats, lack sufficient levels of a specific liver enzyme needed to safely metabolize paracetamol.

What are the symptoms of paracetamol poisoning?

Difficulty breathing, rapid breathing, or blue/grey gums (signs of oxygen deprivation); Swelling of the face, paws, or neck; Lethargy, weakness, and collapse; Vomiting, drooling, and loss of appetite

What should I do if my pet ate Paracetamol Poisoning in Dogs and Cats?

Call your veterinarian or a pet poison control center immediately. This is a time-critical emergency. Do NOT induce vomiting unless specifically instructed by a veterinary professional. If possible, provide the product name, strength (mg), and estimated amount ingested.

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