Suspect poisoning? US: ASPCA Poison Control (888) 426-4435 · UK: 01202 509 000 · Severe symptoms → nearest emergency vet now.

Raw fish thiamine deficiency in dogs and cats

Feeding raw salmon or other fish that contains thiaminase can rapidly deplete a pet’s vitamin B1.

Last reviewed: 2026-09-05 · Reference ranges: ASPCA, Pet Poison Helpline & Merck Veterinary Manual

Treat this as a potential emergency — not a "wait and see" situation.
Contact your vet before symptoms even appear.

US: ASPCA Animal Poison Control (888) 426-4435 · Pet Poison Helpline (855) 764-7661

UK: Veterinary Poisons Information Service 01202 509 000

Why raw fish can be toxic

Thiaminase in raw fish destroys vitamin B1, causing a metabolic crisis.

The enzyme is especially high in salmon, trout and carp that pets may eat after a catch.

Owners often think raw fish is healthy and miss the tiny white flakes on the fur.

Why speed matters

Delaying care significantly worsens outcomes. Some signs appear hours or days later, so "looks fine right now" is not a reason to wait.

Symptoms of raw-fish-thiamine-deficiency poisoning

  • loss of appetite within a day of eating raw fish
  • the pet appears unsteady and may wobble on hind legs by the evening
  • the eyes look cloudy or the pupil is dilated, indicating vision loss
  • rapid breathing and increased heart rate develop in 24-48 hours
  • muscle twitching that can progress to full seizures
  • the pet becomes very weak and may collapse

What to do right now

  1. call your vet urgently, mention raw fish consumption
  2. bring a sample of the fish or describe the type eaten
  3. start giving thiamine supplement if your vet advises, usually via injection
  4. do not give any more raw fish or fish bones
  5. keep the pet warm and monitor breathing until you can get to the clinic
If your pet shows any of the signs above, go to the nearest emergency vet now and call ahead.

Sources & further reading

  • ASPCA Animal Poison Control — pet poison database & dosage references
  • Pet Poison Helpline — toxicology triage guidelines
  • Merck Veterinary Manual — toxicology monographs
  • Vets Now (UK) — emergency toxicosis guidance

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Frequently asked questions

Is Raw fish thiamine deficiency in dogs and cats poisonous to a dog or cat?

Thiaminase in raw fish destroys vitamin B1, causing a metabolic crisis.

What are the symptoms of raw-fish-thiamine-deficiency poisoning?

loss of appetite within a day of eating raw fish; the pet appears unsteady and may wobble on hind legs by the evening; the eyes look cloudy or the pupil is dilated, indicating vision loss; rapid breathing and increased heart rate develop in 24-48 hours

What should I do if my pet ate Raw fish thiamine deficiency in dogs and cats?

call your vet urgently, mention raw fish consumption bring a sample of the fish or describe the type eaten start giving thiamine supplement if your vet advises, usually via injection

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