Suspect poisoning? US: ASPCA Poison Control (888) 426-4435 · UK: 01202 509 000 · Severe symptoms → nearest emergency vet now.

Topical Creams & Ointments

Creams are absorbed through a pet’s thin skin and gut far faster than through human skin — and pets lick them off.

Last reviewed: 2026-09-05 · Reference ranges: ASPCA, Pet Poison Helpline & Merck Veterinary Manual

Treat this as a potential emergency — not a "wait and see" situation.
Contact your vet before symptoms even appear.

US: ASPCA Animal Poison Control (888) 426-4435 · Pet Poison Helpline (855) 764-7661

UK: Veterinary Poisons Information Service 01202 509 000

Why is it dangerous to pets?

Pets have thin skin and a large surface-to-weight ratio, so a topical steroid, hormone gel, pain cream or psoriasis ointment applied for a human can be absorbed in meaningful amounts.

The bigger problem is grooming: a pet that licks the cream off its own or its owner’s skin swallows the whole dose. Vitamin D analogue ointments and calcipotriene are especially dangerous.

Why speed matters

Delaying care significantly worsens outcomes. Some signs appear hours or days later, so "looks fine right now" is not a reason to wait.

Symptoms of topical-creams poisoning

  • Vomiting, drooling, not eating
  • Increased thirst and urination (steroid effect)
  • Weakness, wobbliness, tremors
  • Skin redness or irritation where the cream was applied
  • Kidney-signs and high calcium days later (vitamin D creams)

What to do right now

  1. Wash the cream off with mild soap and warm water before the pet can lick it.
  2. Call your vet or a poison line and name the product — the active ingredient decides the risk.
  3. Never apply human creams to a pet without veterinary advice.
  4. Cover treated skin with clothing or a bandage if a pet shares your bed.
If your pet shows any of the signs above, go to the nearest emergency vet now and call ahead.

Sources & further reading

  • ASPCA Animal Poison Control — pet poison database & dosage references
  • Pet Poison Helpline — toxicology triage guidelines
  • Merck Veterinary Manual — toxicology monographs
  • Vets Now (UK) — emergency toxicosis guidance