Suspect poisoning? US: ASPCA Poison Control (888) 426-4435 · UK: 01202 509 000 · Severe symptoms → nearest emergency vet now.

My dog just ate one of my antidepressant pills (SSRI like Prozac) — what do I do?

Dogs · Emergency guide

Last reviewed: 2026-09-05 · Reference ranges: ASPCA, Pet Poison Helpline & Merck Veterinary Manual

Short answer

This is a serious emergency. SSRI medications can cause serotonin syndrome in dogs, leading to agitation, tremors, high fever, and seizures. Effects can begin within an hour. Do not wait to see if symptoms develop. Contact your veterinarian or an emergency animal hospital immediately. Have the medication bottle handy to tell them the exact drug name and strength. Do not attempt to induce vomiting unless specifically instructed to do so by a veterinary professional.

What is serotonin syndrome?

Drugs such as SSRIs (fluoxetine/Prozac, sertraline), SNRIs and tricyclics raise serotonin levels. When a pet swallows too much, the excess causes agitation, tremors and a dangerously high body temperature — serotonin syndrome.

Why speed matters

Delaying care significantly worsens outcomes. Some signs appear hours or days later, so "looks fine right now" is not a reason to wait.

Signs to watch for

  • Restlessness, agitation, pacing
  • Tremors or shaking, muscle twitching
  • Very high body temperature, panting
  • Vomiting, diarrhoea
  • Seizures, severe rigidity (emergency)

What to do right now

  1. Call your vet or poison control immediately.
  2. Tell them exactly which drug and dose — many are different medicines under one name.
  3. Do not give anything else and do not try home treatment for "calming".
  4. Serotonin syndrome is treatable but needs urgent hospital care — fluids, cooling and specific medicines.
If your pet shows any of the signs above, go to the nearest emergency vet now and call ahead.

Open the full emergency guide: Antidepressant (SSRI) Poisoning →