Short answer
Safe in strict moderation. Guava's fiber slows sugar absorption, making it better than many fruits. Limit to one teaspoon of flesh twice weekly, avoiding the skin and seeds. Monitor blood glucose if trying it for the first time. Never replace prescribed diabetic food with fruit, even low-glycemic options like guava.
Guava — Food safety facts
Safe to share · Cats · full breakdown on the linked food page
Ripe flesh is safe in small amounts. The hard seeds can upset a sensitive stomach.
The full verdict, portion guidance and serving notes are collected on the Guava food facts page.