Suspect poisoning? US: ASPCA Poison Control (888) 426-4435 · UK: 01202 509 000 · Severe symptoms → nearest emergency vet now.

Naproxen Toxicity in Dogs and Cats

Naproxen is a common over‑the‑counter pain reliever that can cause severe organ damage if a pet ingests it.

Last reviewed: 2026-09-05 · Reference ranges: ASPCA, Pet Poison Helpline & Merck Veterinary Manual

Treat this as a potential emergency — not a "wait and see" situation.
Contact your vet before symptoms even appear.

US: ASPCA Animal Poison Control (888) 426-4435 · Pet Poison Helpline (855) 764-7661

UK: Veterinary Poisons Information Service 01202 509 000

Why naproxen is dangerous

Naproxen blocks prostaglandin production which protects the stomach lining and supports kidney blood flow, so the drug erodes the gut and can shut down renal function.

These effects can quickly lead to dehydration, electrolyte imbalance and neurological signs.

Why speed matters

Delaying care significantly worsens outcomes. Some signs appear hours or days later, so "looks fine right now" is not a reason to wait.

Symptoms of naproxen poisoning

  • repeated vomiting starting 1-4 hours after ingestion
  • watery diarrhea appearing within 2-6 hours
  • the pet looks restless and whines when its belly is touched
  • the animal becomes unusually sleepy or weak by the evening
  • the gums turn pale or white as blood pressure drops

What to do right now

  1. call your vet or a pet poison control line immediately
  2. bring the medication bottle or packaging so the exact dose can be identified
  3. keep the pet warm and limit activity while you wait for help
  4. do not induce vomiting because the drug can irritate the stomach and increase risk of ulcer
  5. monitor for seizures or collapse and report any changes to the veterinarian
If your pet shows any of the signs above, go to the nearest emergency vet now and call ahead.

Sources & further reading

  • ASPCA Animal Poison Control — pet poison database & dosage references
  • Pet Poison Helpline — toxicology triage guidelines
  • Merck Veterinary Manual — toxicology monographs
  • Vets Now (UK) — emergency toxicosis guidance

Other poisonings with overlapping signs

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Frequently asked questions

Is Naproxen Toxicity in Dogs and Cats poisonous to a dog or cat?

Naproxen blocks prostaglandin production which protects the stomach lining and supports kidney blood flow, so the drug erodes the gut and can shut down renal function.

What are the symptoms of naproxen poisoning?

repeated vomiting starting 1-4 hours after ingestion; watery diarrhea appearing within 2-6 hours; the pet looks restless and whines when its belly is touched; the animal becomes unusually sleepy or weak by the evening

What should I do if my pet ate Naproxen Toxicity in Dogs and Cats?

call your vet or a pet poison control line immediately bring the medication bottle or packaging so the exact dose can be identified keep the pet warm and limit activity while you wait for help

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