Suspect poisoning? US: ASPCA Poison Control (888) 426-4435 · UK: 01202 509 000 · Severe symptoms → nearest emergency vet now.

My 12-pound dog drank a smoothie that had holly and mistletoe in it, should I be worried?

Dogs · Emergency guide

Last reviewed: 2026-09-05 · Reference ranges: ASPCA, Pet Poison Helpline & Merck Veterinary Manual

Short answer

Yes, this is serious. Both holly and mistletoe are toxic to dogs and can cause vomiting, diarrhea, and abdominal pain. The blended form means your dog likely ingested a concentrated amount of the plant material. Call your vet or the ASPCA Animal Poison Control Center at (888) 426-4435 right away.

Why is this dangerous?

Mistletoe (especially American mistletoe) contains viscumin and phoratoxin, which irritate the gut and can slow the heart. Berries are the most toxic part.

Holly contains saponins and methylxanthines; the spiny leaves also physically injure the mouth and gut. Both are common in December.

Why speed matters

Delaying care significantly worsens outcomes. Some signs appear hours or days later, so "looks fine right now" is not a reason to wait.

Signs to watch for

  • Vomiting and diarrhoea, sometimes with blood
  • Drooling, mouth pain, pawing at the face
  • Abdominal pain, not eating
  • Slow or irregular heart rate (mistletoe)
  • Wobbliness, collapse or seizures in large ingestions

What to do right now

  1. Call your vet or a poison line and say which plant and how many berries or leaves.
  2. Rinse the mouth and check for cuts from holly spines.
  3. Do not induce vomiting if the mouth is injured or the pet is already vomiting.
  4. Use artificial decorations, or hang real ones well above a pet can reach.
If your pet shows any of the signs above, go to the nearest emergency vet now and call ahead.

The step-by-step response, from the first minute to the vet visit, is in our Mistletoe & Holly emergency guide.

Open the full emergency guide: Mistletoe & Holly →